Kvalifikáciu na Veľkú cenu Brazílie 2010 poznačil slabý dážď a mokrý povrch trate, nikto by však nečakal také prekvapenie, ako to nakoniec dopadlo. Pole position si vybojoval Nico Hulkenberg!
Výsledky kvalifikácie na VC Brazílie 2010:
| Pozícia | Jazdec | Tím | Q1 | Q2 | Q3 | Strata |
| 1 | Nico Hulkenberg | Williams-Cosworth | 1:20,050 | 1:19,144 | 1:14,470 | |
| 2 | Sebastian Vettel | RBR-Renault | 1:19,160 | 1:18,691 | 1:15,519 | 1,049 |
| 3 | Mark Webber | RBR-Renault | 1:19,025 | 1:18,516 | 1:15,637 | 1,167 |
| 4 | Lewis Hamilton | McLaren-Mercedes | 1:19,931 | 1:18,921 | 1:15,747 | 1,277 |
| 5 | Fernando Alonso | Ferrari | 1:18,987 | 1:19,010 | 1:15,989 | 1,519 |
| 6 | Rubens Barrichello | Williams-Cosworth | 1:19,799 | 1:18,925 | 1:16,203 | 1,733 |
| 7 | Robert Kubica | Renault | 1:19,249 | 1:18,877 | 1:16,552 | 2,082 |
| 8 | Michael Schumacher | Mercedes GP | 1:19,879 | 1:18,923 | 1:16,925 | 2,455 |
| 9 | Felipe Massa | Ferrari | 1:19,778 | 1:19,200 | 1:17,101 | 2,631 |
| 10 | Vitaly Petrov | Renault | 1:20,189 | 1:19,153 | 1:17,656 | 3,186 |
| 11 | Jenson Button | McLaren-Mercedes | 1:19,905 | 1:19,288 | ||
| 12 | Kamui Kobayashi | BMW Sauber-Ferrari | 1:19,741 | 1:19,385 | ||
| 13 | Nico Rosberg | Mercedes GP | 1:20,153 | 1:19,486 | ||
| 14 | Jaime Alguersuari | STR-Ferrari | 1:20,158 | 1:19,581 | ||
| 15 | Sebastien Buemi | STR-Ferrari | 1:20,096 | 1:19,847 | ||
| 16 | Nick Heidfeld | BMW Sauber-Ferrari | 1:20,174 | 1:19,899 | ||
| 17 | Vitantonio Liuzzi | Force India-Mercedes | 1:20,592 | 1:20,357 | ||
| 18 | Adrian Sutil | Force India-Mercedes | 1:20,830 | |||
| 19 | Timo Glock | Virgin-Cosworth | 1:22,130 | |||
| 20 | Jarno Trulli | Lotus-Cosworth | 1:22,250 | |||
| 21 | Heikki Kovalainen | Lotus-Cosworth | 1:22,378 | |||
| 22 | Lucas di Grassi | Virgin-Cosworth | 1:22,810 | |||
| 23 | Christian Klien | HRT-Cosworth | 1:23,083 | |||
| 24 | Bruno Senna | HRT-Cosworth | 1:23,796 |
